Nature 411, 595599
When oocytes experience DNA damage due to chemotherapy, radiotherapy, environmental toxins, or natural aging, members of the p53 family, particularly the TAp63 isoform, are activated
PAH pathogenesis involves multiple interrelated mechanisms, including genetic predisposition, endothelial dysfunction, inflammation, oxidative stress, and vascular remodeling
Pigment Cell Res 15:6266
The study, conducted using electronic health records from the TriNetX network between 2017 and 2024, excluded patients with prior neurodegenerative or cerebrovascular conditions and used propensity score matching to balance baseline characteristics
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