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[119] fabricated a bilateral microneedle patch to deliver cyclodextrin-based metalorganic framework (CD-MOF)-encapsulated DXMS and paeonol to overcome the disadvantages of conventional intranasal administration, which not only enhanced the therapeutic effect of the drug but also reduced mast cell degranulation and modulated Th17/Treg cell homeostasis

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In a separate study, Sun (2023) formulated a clobetasol propionate-loaded niosomal gel for topical PsO treatment