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Biocompatibility and toxicity concerns Unlike traditional drugs, emerging nanomaterials can exhibit unpredictable reactions within the human body, posing challenges related to biocompatibility and toxicity [229, 230]

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thymidylate/methionine biosynthesis)

The gastrointestinal consequences of an accidental double dose can be severe and prolonged

Research protocols have used multiple administration routes, including intraperitoneal, subcutaneous, intramuscular, intravenous, and oral delivery , strictly within preclinical research settings