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Some researchers, especially those with higher body weight or prior GLP-1 exposure, may not notice any appetite or metabolic changes at 2mg

Compounds 40 and 41 were identified through a combination of docking-based virtual screening and pharmacophore modeling from an in-house oncology compound library

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PC: Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Supervision, Writingoriginal draft, Writingreview and editing

Neither compound is processed through CYP450 liver enzymes, eliminating the most common mechanism for drug-drug interactions

Absence of evidence that Slc12a8 encodes a nicotinamide mononucleotide transporter