We covered much of the basics in our previous post on the topic, The Wegovy Pill: A Needle-Free GLP-1 Weight Loss Option, including the biggest area of intrigue: dosage translations from injections to pills and vice versa
Ingredients Purified Water, Citric Acid, Potassium Sorbate (Preservative), Sodium Benzoate, Sucralose, Natural & Artificial Flavor
Meanwhile, GLP-1R has been shown to exist in human liver cells
What may benefit one individual could pose a risk to another
A small crossover study (N=28) found that exenatide co-administration reduced levothyroxine Cmax by 16% without significantly changing AUC [13]
Abushanab D, Liew D, Marquina C, Al-Badriyeh D, Ademi Z (2022) Cost-effectiveness of empagliflozin and metformin combination versus standard care as first-line therapy in patients with type 2 diabetes mellitus