Overall, after 68 weeks, 83% of adults taking Wegovy lost 5% or more of their weight compared to 31% of adults taking a placebo
But buried in the data is a detail that matters more than most people realize: lean mass accounted for 26-40% of total weight lost in GLP-1 trials
Ozempic has been used off-label to treat conditions like PCOS
Body weight reduction with tirzepatide by sex: a subgroup analysis of the SURMOUNT clinical trials
It has recently been shown that GLP-1R neurons in the dorsomedial hypothalamic nucleus regulate pancreatic activity by affecting the dorsal motor nucleus of the vagus, specifically lowering blood glucose levels by increasing insulin release (Huang et al., 2022)
As usual, your physical therapist will keep a close watch on your progression of improvement after surgery, and if you are not improving as we would expect, or your pain is not well controlled during your rehabilitation, we will ask you to return to your surgeon for follow-up to ensure there are no complicating factors impeding your recovery