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Amid the Biden administrations recent proposal to expand obesity drug coverage under Medicare and Medicaid, experts at Real Chemistry examined which state Medicaid programs currently cover GLP-1s approved to treat obesity and how much they are spending

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Rather than trying to force a peptide through the gastrointestinal barrier using formulation technology, several research groups asked whether a small, non-peptide molecule could be designed to activate the GLP-1 receptor directly

Additionally, Arg at the 34th position is replaced with Lys to accommodate site-specific acylation