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In tumor cells, chemotherapy-induced senescence led to elevated ceramide biosynthesis [26, 27]

[DOI] [PubMed] [Google Scholar] 14.Salehi M, Gastaldelli A, D'Alessio DA

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Ann N Y Acad Sci 1259:95103

4.1 Body weight and fat mass Most studies showed that dietary supplementation of a high-fat diet (HFD) with 5% (w/w) sodium butyrate significantly reduced body weight gain in mice compared with that induced by the HFD alone (34, 116122), whatever a long-term supplementation for up to 16weeks (116, 120) or a short-term supplementation for down to 4 weeks (117)