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The four-week increment is a minimum

This alcohol-induced steatosis is further compounded by the systemic insulin resistance from obesity, which independently drives an influx of FFA to the liver

Effect of truncated glucagon-like peptide-1 (proglucagon78107 amide) on endocrine secretion from pig pancreas, antrum, and nonantral stomach

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10.1038/s41467-023-44067-4 34 KanmaniP.VillenaJ.LimS.-K.SongE.-J.NamY.-D.KimH

1 Introduction Obesity has become a threat to human health worldwide, with the rate of obesity more than 20% in some areas ( Glucagon-like peptide-1 (GLP-1), a peptide hormone derived from proglucagon, is generated in the gut and brain stem primarily through the action of prohormone convertase 1/3 ( However, GLP-1 is rapidly decomposed by dipeptidyl peptidase 4 after secretion under physiological conditions (Tamborlane et al., 2019