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Within the integrated framework depicted in Figure 3, modulation of adipocyte lipid metabolism and lipolysis represents an upstream mechanistic axis linking semaglutide treatment to downstream improvements in ectopic lipid deposition and systemic insulin sensitivity

There was a statistical difference in C4 between groups

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Occasional reports include temporary fatigue or lethargy (5-10% of users), mild headaches in the first few days of use, slight water retention, or transient flushing at injection sites

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