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[10] [11] Therefore, any B12 deficiency detected in a patient taking Mounjaro may actually be attributable to metformin rather than tirzepatide itself

It also aids in producing neurotransmitters, which are chemicals that help communicate between neurons in the brain, improving brain function

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By preserving NAD+ and SAM in both fat and muscle tissue, NNMT inhibition may theoretically address the metabolic dysfunction underlying both excessive fat storage and impaired muscle maintenance