Specifically, a better delineation of the embryonic and postnatal roles of IGF-1 signaling in promoting skeletal health is much warranted and will require the use of animal models carrying inducible Cre recombinase transgenes that allow time- and cell-specific deletion of the gene in question
Ishikawa A, Homma Y
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Furthermore, WB analysis was conducted on extracts from the aortas of aging mice, showing consistent results with in vitro experiments: increased expression of p-P53 and decreased expression of total P53 after FOXO4-DRI treatment
Mittal AK, Chisti Y, Banerjee UC
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