How to modify beginner resistance training programs for older individuals to prioritize safety and gradual progress [1:35:30]
"The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration." J Appl Physiol
Whats Coming: The Future of SUD Pharmacotherapy Emerging therapies for substance use disorder (SUD) are expanding beyond traditional medications, with early studies showing promise across several novel approaches
Kang D-M, Park WS, Kim H-J, Jeong W-J
10.1093/ecco-jcc/jjaa182 43 TannoM.SakamotoJ.MiuraT.ShimamotoK.HorioY
What they found: In normal obese mice: AOD-9604 reduced body fat by 21 % vs placebo, hGH by 24 % The AOD-9604 effect was fully dependent on the 3-adrenergic receptor , in knock-out mice no effect The hGH effect was partly independent of 3-AR , in knock-out mice there was still ~10 % fat reduction AOD-9604 did not raise IGF-1 (control level), whereas hGH raised IGF-1 by 80 % No changes in growth, organ weights (except adipose tissue), fasting insulin Why it matters: The study provided the mechanistic basis for AOD-9604 and confirmed the key business hypothesis: it is possible to separate the lipolytic effect of GH from its growth effect