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Biotin does not harm the thyroid itself, but it can cause significant interference in thyroid blood tests (TSH, T4, and T3)

The 30 mL vial format is commonly used in clinical, pharmacy, and healthcare settings where sterile preparation is required under appropriate direction

Ethics declarations Competing interests The authors declare no conflicts of interest with the exception of YZ who is the shareholder for UNOMI Company

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enzymatic transthioesterification can be achieved by reacting glutathione with an appropriate acyl ester of coenzyme A (CoA) followed by purification from the water phase by HPLC or by chemically reacting glutathione with the corresponding acyl halide