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Therefore, the main objective of this review is to highlight the latest discoveries of bioactive synthetic substances on XO inhibition and increase understanding of the potential uses of new molecules to treat hyperuricemia over the last 5 years

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In keeping with recommendations issued by NICE, the FDA, and various other obesity experts, GLP-1s are often administered in tandem with holistic, multidisciplinary behavioural and lifestyle interventions, such as counselling, progress monitoring, and peer support

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The pooled random-effects estimate showed no difference between classes: RR 1.01 (95% CI 0.841.23), with the overall effect non-significant ( Z = 0.15, p = 0.88)