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In parallel, PCS samples also demonstrated continued elevation of antioxidant and redox-buffering enzymes, including superoxide dismutase (SOD1/SOD2) and glutathione-related enzymes (GLRX1/2/3, GSTA2, GSTK1, GSTP1, GPX3), along with TXNDC family proteins, MSRB1, and ALDH-family detoxification enzymes ( Figure 6E )