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Stimulant / Irritant Laxatives Examples: Senna, Bisacodyl, Castor oil Mechanism: Stimulate enteric nerves increase peristalsis Uses: Short-term constipation, bowel prep Adverse Effects: Abdominal cramps, electrolyte imbalance, melanosis coli (long-term senna use) 4

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By 2021 to 2023, those figures ballooned to 40.3 percent and 9.4 percent, or a total of 128.4 million adults

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