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As our understanding deepens, we can expect even more powerful, targeted, and safer medications that harness the full potential of GLP-1 biology

Some will continue to stay on the same dose of medication

The challenge is what happens when these mechanisms are no longer active

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There is also uncertainty whether or not weight loss will remain even with continued usage of the medication after five years

Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease