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The rules have changed dramatically, and those changes directly affect availability, legality, and the future of compounded formulations

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Semaglutide may cause leg cramps due to its effects on glucose levels, electrolytes, hydration, blood flow, and muscle function

Medicare GLP-1 Bridge (Medicare members) Starting July 1, 2026, eligible Medicare members can access Wegovy for weight loss at $50/month through the Bridge program, which operates outside Part D

Both sit in the "longevity" aisle

It met its primary endpoint, with a statistically significant improvement in pain with Xiaflex versus placebo, as measured by the Average Daily Pain Intensity on the Numeric Rating Scale (NRS), which Keenova said was a "clinically meaningful" result