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502 Approximately 10% of ALS cases are familial ALS, with various disease-causing genes identified, including superoxide dismutase 1 (SOD1), chromosome 9 open reading frame 72 (C9ORF72), and fused in sarcoma (FUS)

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Furthermore, (-)-Vestitol has been identified as an -glucosidase inhibitor and can bind to the PPAR- receptor, suggesting potential therapeutic effects for diabetes mellitus [39, 40]