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The pharmcodynamic effects of dutasteride include a reduction in total serum prostate-specific antigen (PSA), an increase in total testosterone, an increase in thyroid-stimulating hormone (TSH), and a decrease in total serum DHT

Interpretation should remain rigorously compartment-aware and coupled to source attribution (e.g., NOX versus mitochondrial origin) to avoid conflating cause with consequence (Zhang et al

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Furthermore, MPs induce gut dysbiosis by decreasing probiotic bacteria and increasing pro-inflammatory

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