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In general, the changes were milder in the cerulein-induced AP model (Figures 3eh) than in the model of L-arginine-induced AP (Figures 3ad)

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PMID 15189123

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The trial was terminated early by the studys data safety and monitoring board because prespecified futility boundaries were crossed

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For example, H 2 O 2 /O/OH can oxidize amino acid residues in proteins, leading to changes in protein structure and function [203]

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The use of total effect indices negates the need for determining higher order interactions which can be computationally expensive

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