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Regarding the mechanisms, prolonged periods of fasting state are characterized by a metabolic switch from glucose dependency to elevation of lipid metabolism, including free fatty acid usage and production of ketone bodies in the liver (Hofer et al., 2022)

Table 3 Group differences GSH and peripheral blood markers

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Reduced expression of the ferroptosis inhibitor glutathione peroxidase-4 in multiple sclerosis and experimental autoimmune encephalomyelitis