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The treatment is mostly painless, though Harvard Health notes slight discomfort if the doctor or nurse requires multiple attempts to locate a vein for the IV

Comparatively, treatments like Botox and dermal fillers offer temporary solutions to aging symptoms

However, when used as a long-term strategy, it often fails to resolve underlying drivers of painand may introduce new problems over time

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Studies have shown that VDR deficiency severely impairs epidermal differentiation, leading to aberrant keratinization and disorganized expression of differentiation markers such as K1, K10, and involucrin