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Baseline renal function was normal or mildly impaired in 88% of patients and moderately impaired in 11% of patients (mean eGFR 82 mL/min/1.73 m)

10.1038/cddis.2014.581 Cell

Furthermore, GLP-1 agonists should not be advised for individuals with serious gastrointestinal conditions like gastroparesis

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These medications, known as GLP-1 receptor agonists (GLP-1-RAs), offer promising therapeutic options for type 2 diabetes and obesity-related conditions, including cardiovascular disease (CVD) and non-alcoholic fatty liver disease (NAFLD) (6)