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These dermal alterations are closely linked to skin photoaging including the hyperpigmented lesions

2021;54(3):e12993

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Feature: Targets: Semaglutide: GLP-1 Tirzepatide: GLP-1 + GIP Retatrutide: GLP-1 + GIP + Glucagon Max Weight Loss: Semaglutide: ~15% Tirzepatide: ~22% Retatrutide: 24.2%+ Energy Expenditure: Semaglutide: Low Tirzepatide: Moderate Retatrutide: High Muscle Preservation: Semaglutide: Moderate Tirzepatide: Moderate Retatrutide: Better Dosing Frequency: All: Weekly The addition of glucagon receptor activation gives Retatrutide a unique fat-burning advantage, making it ideal for visceral fat reduction and metabolic reset protocols

Ignacio Alfonso for their critical reading of the manuscript

Part 2 of a 3-part series From antibiotic overuse to microbiota transfer therapy: what 25 years of research reveals about the autistic gut By Dr