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Yes, significantly

Metformin, sulfonylureas, and generic pioglitazone remain first-line agents on TennCare formularies

Moreover, in mouse brain mitochondria another study showed that OGC and DIC are both expressed in cortical neurons and astrocytes (Wilkins et al., 2013)

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treating low glucose under clinical guidance may resolve the episode

Oral formulations are forecast to expand at a 6.39% CAGR between 2026 and 2031 as products like orforglipron near approval