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EC50 determination is reliable Scenario B: 85% pure IGF-1 LR3 stock (1 mg/mL) At a nominal concentration of 100 ng/mL in assay, actual IGF-1 LR3 = ~85 ng/mL Remaining ~15 ng/mL consists of potentially inhibitory, partially active, or bioactive contaminant species Dose-response curve is shifted

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El primero a mencionar se realiz en 14 pacientes con diabetes mellitus tipo 2, con mal control metablico, el grupo tena edad media de 54 aos con tiempo de evolucin de la enfermedad de 18.5 aos, HbA1c promedio de 10.1% y peso de 113.3 kg

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Engineered to retain the lipolytic activity of full-length hGH without its hyperglycemic or mitogenic effects

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