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Typical inclusion criteria for the SUSTAIN and PIONEER trials were age 18 years, a diagnosis of T2D at least 90 days prior to screening, and inadequate glycemic control within a specified HbA 1c range ( Table 1 )

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The benefits of triple agonism extended also to MASLD in a subgroup of 98 people, fat content normalised in approximately 90% of people receiving the highest retatrutide doses [82]

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