Positive action of high doses of thiamine under metabolic perturbations including surgeries (48, 115, 149, 153155) suggest that cellular protection and/or repair requiring cell differentiation, increase demand of thiamine
If that doesnt work, theyll recommend weight loss medications like semaglutide (Wegovy) or tirzepatide (Zepbound)
Raghuveer P, Shanthi D, Kumar TU, Rao PL, Sriharsha K, Madhuri D, et al
FDA-approved uses: Off-label uses: Weight management in non-diabetics Metabolic health improvement.[diet.mayoclinic] How Does Semaglutide Work for Weight Loss
Ongoing research is exploring: Combination Therapies: Investigating the potential of combining GLP-1 agonists with other medications (such as GIP receptor agonists) to achieve even greater weight loss and metabolic benefits
A loss of muscle mass is counterproductive to what GLP-1 users are trying to accomplish