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Single-nucleus RNA-sequencing shows opposing effects of GIPR agonism and antagonism in the hindbrain, with antagonism, but not agonism, mimicking GLP-1R signalling and with GIPR antagonism and GLP-1R agonism both regulating gene programmes implicated in synaptic plasticity

doi: 10.3389/fendo.2023.1073878 161

HjorthEZhuMToroVVedinIPalmbladJCederholmTet alOmega-3 fatty acids enhance phagocytosis of alzheimers disease-related amyloid-42 by human microglia and decrease inflammatory markers

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It may also exhibit synergistic effects with statins and activate pathways such as AMP-activated protein kinase (AMPK), contributing to its observed health benefits [112,113,114]