4, 5, and 6 are prepared with the appropriate amounts of a JNK inhibitor, such as any one of the JNK inhibitors described herein, and medium chain triglyceride (CRODAMOL, GTCC-LQ-(MV), PhEur) as shown in the below table (Table D).Formulations The formulations are prepared by adding the target weight percentage of the JNK inhibitor to the appropriate amount of medium chain triglyceride
The pH is 5.7 (4.5 to 7.0)
J Biol Chem 276:64796484 Ronnebaum SM, Joseph JW, Ilkayeva O et al (2008) Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism
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