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On PND 24 and 31 the interstitial cell number of rhGH-treated rat testes was not significantly different from those of controls (Fig

Tando T, Hirayama A, Furukawa M, Sato Y, Kobayashi T, Funayama A, Kanaji A, Hao W, Watanabe R, Morita M, Oike T, Miyamoto K, Soga T, Nomura M, Yoshimura A, Tomita M, Matsumoto M, Nakamura M, Toyama Y, Miyamoto T (2016) Smad2/3 proteins are required for immobilization-induced skeletal muscle atrophy

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With the progression of HT, these imbalances intensify further, with a substantial decline in beneficial bacteria and heightened dominance of pathogenic bacteria, including Streptococcus , Enterobacteriaceae and Acinetobacter (Sessa et al., 2025)