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Long-term kidney outcomes among users of proton pump inhibitors without intervening acute kidney injury

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While both agents struggled with the inherent GI burden typical of GLP-1RAs, efpeglenatides limitations were largely dose-related and within manageable expectations, whereas taspoglutides combination of severe immunogenicity and hypersensitivity reactions rendered it clinically unviable

GLP-1 medications reduce progression from prediabetes to diabetes by 72% compared to control groups 6

Published August 4, 2023