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TGP sybodies enabled affinity purification of membrane proteins As part of the GFP toolkit, single-chain camelid antibodies (nanobodies) 67,68 and designed ankyrin repeat proteins (DARPins) 69 are available for affinity chromatography, contributing to the purification of several high-profile membrane proteins for structure determination 70,71,72,73,74,75

Of late, multiple transcription factors such as TFAP2C, p53, AP-1, STAT, Nrf2, HIF-1, and C/EBP have been linked with the transcriptional regulation of seleno-GPxs [8, 21,22,23,24]

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Treatment duration typically runs six to twelve weeks