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The engineering of bimodal molecules that integrate GLP-1R agonism with other pain-related mechanisms, such as N-methyl-D-aspartate (NMDA) receptor antagonism, may be especially beneficial for pain management [61]

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You might describe it as sharp, burning, or electric-shock-like sensations that start in your lower back and shoot down one leg

Key Takeaway: If you start a GLP-1 medication and lose more than 5-10% of your body weight, you must work with your GP to monitor your thyroid function

The gutbrain axis and the microbiome: mechanisms and clinical implications