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Journal of Molecular Medicine , 95(3), 323333.

Stimulation of intestinal calcium absorption by orally administrated vitamin D3 compounds: a prospective open-label randomized trial in osteoporosis

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Indeed, the most frequent mutations in the SCL12A3 gene are those that result in lack of proper glycosylation of the NCC protein which prevents its trafficking to the membrane or interferes with its ability to transport Na + and Cl