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GH secretagogues require more cautious dosing because cancer screening becomes more important as baseline cancer risk rises with age

The form of the activation was derived by nonlinear regression on the data in [23, 24]

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While surveying the literature in preparation of this manuscript we have also noticed and reported an increasing interest in the role that GSTs play in neurodegeneration, where isozymes belonging to the family may be either up-regulated, mutated or absent, according to the different diseases