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Key Takeaways GHK-Cu is a copper binding tripeptide, not a hormone It modulates extracellular matrix remodeling Its effects are local rather than endocrine Human evidence supports skin and wound applications Systemic anti aging claims exceed available data Sources Pickart L, Thaler MM
Remain there for a full 4 weeks, then re-attempt escalation
Dose-by-dose weight loss in Phase 2 (NEJM) Phase 2 NEJM weight loss by dose, 24 and 48 weeks Dose 1 mg 24 weeks -7.2% 48 weeks -8.7% Dose 4 mg 24 weeks -12.9% 48 weeks -17.5% Dose 8 mg 24 weeks -15.7% 48 weeks -22.8% Dose 12 mg 24 weeks -17.5% 48 weeks -24.2% Dose Placebo 24 weeks -1.6% 48 weeks -2.1% Source: Jastreboff et al., NEJM 2023
BMJ Open Diabetes Res Care 10(1):e002517 Pi-Sunyer X et al (2015) A randomized, controlled trial of 3.0 mg of liraglutide in weight management
Astaxanthins antioxidant activity is due to its highly conjugated structure, noted David Padr, Manager of the Nutraceuticals Business of LLS Health