We support a thorough approach to weight control, so it is always our priority to have a thorough discussion with our patients about the most effective weight loss strategies for them
Key results (52 weeks): Max walking distance 13% (median gain: +26 m) Pain-free walking distance 11% (median gain: +14 m) QoL (VascuQoL-6) improved significantly Lower rates of rescue treatment and (HR 0.46) Effects persisted 5 weeks after treatment stopped Better anklebrachial index, HbA1c, and weight loss (5.2 kg) Safety: Well tolerated Serious adverse events similar to placebo (19% vs 20%) Discontinuation due to AEs: 7% (semaglutide) vs 4% (placebo) No treatment-related deaths How does it compare
GLP-1-based medications are prescribed for the management of type 2 diabetes and weight management
KPV is derived from alpha-MSH but does not bind melanocortin receptors (MC1R, MC3R, MC5R)
Jardiance warnings Jardiance increases the risk of diabetic ketoacidosis (DKA), which is a life-threatening condition
Topiramate appears to enhance this feeling, which can prevent overeating