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Fluctuations in intraocular pressure (IOP), insufficient blood supply to the optic nerve, malnutrition, trauma, hypoxia-induced inflammatory responses, and degeneration of RGCs are the basic factors for its onset (123), among which the increase in pathological intraocular pressure (ph-IOP) and the death of RGCs are the key factors (124)
Curcumin and quercetin ameliorated cypermethrin and deltamethrin-induced reproductive system impairment in male wistar rats by upregulating the activity of pituitary-gonadal hormones and steroidogenic enzymes
