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These results suggested that GLP-1 expression was gradually decreased in CM, and also revealed that although the protein expression of GLP-1R was upregulated after NTG stimulation, the amount of GLP-1Rs that can be activated was decreased, so the activity of GLP-1R in the TNC in CM model was actually inhibited
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In comparison to age-matched controls there was no significant difference in leucocyte infiltration in the kidney and only slightly increased numbers of macrophages were present in the renal cortex [57]
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