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These include: Tier 2 services : Community-based lifestyle interventions Tier 3 services : Specialist multidisciplinary teams for complex obesity Tier 4 services : Bariatric surgery assessment and procedures Referral criteria for these services are outlined in NICE guideline CG189 for obesity management

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Compared with DPP4i use, GLP-1RA therapy was associated with a 20% lower risk of overall dementia (hazard ratio [HR] 0.80

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