The dose is dependent on how well you tolerate the medication
It gains entry into cells using its spike protein to fool a receptor on our cells called ACE2
Fluid Balance and Dehydration Risk Semaglutide can also cause nausea, vomiting, and diarrhea, especially during the first few weeks of use
Cancer Risk A review and discussion stated: ROS production is significantly increased in cancer cells because of mitochondrial dysfunction, altered metabolism, and frequent genetic mutations, resulting in an accumulation of large amounts of oxidized protein, DNA, and lipids as an adaptive response, cancer cells harbor elevated levels of ROS-scavenging molecules
Retatrutide may be more relevant for research into multi-receptor metabolic coordination
From what I have seen and experienced, many people notice measurable weight loss within the first three months, especially once they reach a stable dose