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"While the drug's role in promoting weight loss is well-established, what's particularly exciting is its potential to also reduce the frequency of HS flare-ups, contributing to the notable improvements observed in patients' quality of life," Lyons added

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Although the term PEM allows one to deal with diagnostically challenging pigmented melanocytic tumors, for which a reliable distinction between melanoma and an unusual pigmented nevus is difficult or impossible by light microscopic examination alone, we caution against labeling lesions as PEM, which previously would have been diagnosed as benign EBN or pigmented dermal spindle and epithelioid cell nevus