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In addition,meta-analysessuggest that GLP-1 RAs may actually improve bone density in the lumbar spine and hip compared with controls. Any rapid weight loss, including from calorie restriction or bariatric surgery, is likely to be associated with some bone loss, so I do not think blaming GLP-1s is the answer, she added

These medications don't just suppress appetite in the traditional sense they work directly on the hormonal pathways that regulate hunger, fullness, and metabolism, producing levels of weight loss that were previously only achievable through bariatric surgery

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These issues highlight why self-medicating is not advised and medical oversight is crucial

Clinical studies suggest Se may have potential in mitigating cognitive decline (111,134)