Orforglipron (LY3502970), a novel, oral non-peptide glucagon-like peptide-1 receptor agonist: a phase 1b, multicentre, blinded, placebo-controlled, randomized, multiple-ascending-dose study in people with type 2 diabetes
Educational only
Patients with BMI below 27 generally do not meet standard FDA-approved criteria for Tirzepatide weight loss treatment
It consists of eight pivotal trials running in parallel, enrolling more than 5,800 participants in total across the weight-management and diabetes indications, plus a separate roughly 10,000-patient cardiovascular outcomes trial
The short answer is yes, but getting this wrong is expensive
TRANSCEND-T2D-1 reported dysesthesia in 2.34.5% of participants