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Indirect mechanisms that might influence mental health include: Metabolic improvements : Better glycaemic control and weight loss often improve quality of life and psychological wellbeing Gastrointestinal symptoms : Persistent nausea or discomfort may negatively affect mood Nutritional changes : Reduced food intake could affect overall wellbeing Body image and identity : Rapid physical changes may trigger psychological adjustment challenges Ongoing research continues to explore the complex relationship between metabolic medications and mental health, but current evidence does not support a direct depressogenic effect of Ozempic

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