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FIGURE 5 3.6 Effect of DXN and TIR on antioxidant enzymes in the rat brain In the group treated with DXN, the relative expression levels of SOD and GPx were significantly reduced correlated to the control group, with p -values of less than 0.01 and 0.0001, respectively

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This disequilibrium can result in cellular injury and is implicated in the pathogenesis of neuropathy, wherein nerve damage arises from sustained OS

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This study reports the identification of VHL tumour suppressor protein as a key molecule in the oxygen-dependent degradation of HIF