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Other organizations also have developed guidance on how to best manage immunotherapy side effects

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MT, as an endogenous antioxidant, is capable of crossing the BBB, scavenging free radicals, and upregulating the expression of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GPx), thereby enhancing antioxidant capacity (Banach et al., 2011)

VEGF tumorigenesis was avoided and counteracted (Sikiric et al., 1997c), and inhibition of the growth of several tumor lines and counteraction of tumor cachexia (Sever et al., 2019) were observed

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